Oh Ya,,,308 and 06 are by far my go-to's for just about everything. There very versatile with all the projectiles and loads available for them. Hell with a 06,,you can damn near shoot everything from squirrels to elephants with them. A 6.5x55 and 270 are no slouches either, those are my,next,, 2 favorite calibers for hunting and long range!! There is a bunch of wildcats out there that are impressive too,, but all around 308 and 06's are the "just the ticket" and hard to beat for all around use, IMO. And it won't drive ya crazy finding brass and projectiles for them, like it does for wildcat calibers. I got away from all the wildcat stuff years ago.