I think HC's 45-70 build should pack enough punch for satisfy most mortal men . it can be loaded to what ever one thinks is safe and beyond. the 458x2 would be another round to consider & uses a smaller bolt face. I just think the huge cost of .375 ruger brass not to mention the difficulty of building it and the added expense of all the extra parts that arn,t standard make it a build that is not worth it UNLESS you have to have a AK in that specific calibur and dont care abiout the cost. I would personally rather have a Bar browning in something like 300 win mag for the money. A 50 BMG is another that for around $1000 up starts to become more attractive as some of these more exotic AK builds start to get pricey$$$.