A serious hike in-out trek for camping and fishing in so cal is a trek to Siberia Creek. It is an immense loss gain hike of over 2500feet in a 2-3 mile stretch from either direction you take to get there. You could also do a car shuttle. The creek has wild trout, catch and release single barbless regs apply.
Another spot is a trek to fishermans camp along deep creek. This is a nice loop hike and deep creek is well known for great swimming holes as well. The fishing again is for wild trout, catch and release single barbless regs apply,